Bone Formation in Carotid Plaques

Bone Formation in Carotid Plaques

Background and Purpose—Bone formation and dystrophic calcification are present in carotid endarterectomy plaques. The clinical significance of these findings is unknown. The purpose of this study was to determine whether bone formation and extensive dystrophic calcification are associated with stable plaques and protective against ischemic vascular events. Methods—Carotid endarterectomy plaques...

Bone formation in carotid plaques: a clinicopathological study.

BACKGROUND AND PURPOSE Bone formation and dystrophic calcification are present in carotid endarterectomy plaques. The clinical significance of these findings is unknown. The purpose of this study was to determine whether bone formation and extensive dystrophic calcification are associated with stable plaques and protective against ischemic vascular events. METHODS Carotid endarterectomy plaqu...

Truth of Floating Carotid Plaques

The floating plaque in carotid artery is an uncommon condition that can be detected by a duplex ultrasonography scan and is a high-risk factor for embolic cerebrovascular disease. The histopathological features of floating plaque in carotid artery vary. To the best of our knowledge, there is still considerable controversy about the treatment of floating carotid plaque. In this case, the floatin...

Tissue Characterization of Carotid Plaques

ABCA1 expression in carotid atherosclerotic plaques.

BACKGROUND AND PURPOSE The ATP-binding cassette transporter A1 (ABCA1) facilitates cholesterol efflux from cells, a key process in reverse cholesterol transport. Whereas previous investigations focused on mutations causing impaired ABCA1 function, we assessed the role of ABCA1 in human carotid atherosclerotic disease. METHODS We compared the mRNA and protein levels of ABCA1, and one of its ke...